PolyDADMAC is used for controlling disturbing substances in the papermaking process. It provides superior fixing of pitch from mechanical pulp and of latex from coated broke. Used in the short circulation of a paper mill to enhance retention and dewatering. In addition, it can be used to improve the efficiency of disk filters and flotators, and for cationization of fillers to provide maximal filler retention.

PolyDADMAC can also be used as a flocculant to improve soap separation process in the evaporation plant of kraft pulp mills thus contributing to higher tall oil yield.